Methanol → 2-Methoxycyclohexanone

HRID 1730439Notes

Reaction equation

HRID 1730439 reaction equation
Cl[CH:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C:3]1=[O:8].[CH3:9][OH:10]>>[CH3:9][O:10][CH:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C:3]1=[O:8]

Participants

3

Reactant 2

HCID 887MethanolHCID 132032-Chlorocyclohexanone

Product 1

HCID 1109982-MethoxycyclohexanoneYield 90%

Procedure

2-methoxycyclohexanone was prepared as in Example 4, by dissolving 98 gm. 2-chlorocyclohexanone in 750 ml. methanol and heating the solution in a sealed vessel at 160° C. for 15 minutes. The conversion was 98-99% with a yield of greater than 90%.

Workup

  1. dissolutionby dissolving 98 gm

Sources & evidence

ORD record
ord-4b3b9878e5cc43d99bf558b80deae5ff
Source dataset
uspto-grants-1976_11
Patent number
US03992452

Reaction notes

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