Benzene → HCID 21498286, compound

Participants

Reaction Steps

A solution of 1-benzyl-1,2,3,6-tetrahydro-3-methyl-4-pyrolidino-pyridine (14 g) and propargyl bromide (6 g) in dry benzene (50 ml) was stirred at room temperature under nitrogen for 40 hours. The mixture was then heated on a steam bath for one-half hour with water (200 ml). The organic layer was collected, dried over magnesium sulphate and evaporated, leaving 11.6 g of the crude title compound (about 50% by g.l.c.) as a red oil.

Provenance & Evidence