4-Methoxybenzylamine → HCID 21498284, compound

HRID 1730514Notes

Reaction equation

[CH2:1]([CH:5]1[C:10](=O)[CH:9]([CH3:12])[CH2:8][N:7]([CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH2:6]1)[C:2]([CH3:4])=O.[CH3:20][O:21][C:22]1[CH:29]=[CH:28][C:25]([CH2:26][NH2:27])=[CH:24][CH:23]=1>>[CH2:13]([N:7]1[CH2:8][CH:9]([CH3:12])[C:10]2[N:27]([CH2:26][C:25]3[CH:28]=[CH:29][C:22]([O:21][CH3:20])=[CH:23][CH:24]=3)[C:2]([CH3:4])=[CH:1][C:5]=2[CH2:6]1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

Reactant 2

HCID 754524-Methoxybenzylamine

HCID 21498268HCID 21498268, compound

Product 1

HCID 21498284HCID 21498284, compound

Procedure

Using a procedure analogous to Example 3, 3-acetonyl-1-benzyl 5-methyl-4-piperidone may be reacted with p-methoxybenzylamine to give thetitle compound.

Workup

customto give thetitle compound

Sources & evidence

ORD record: ord-9933f6dea395468f969103ce98602624
Source dataset: uspto-grants-1976_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03992544

Reaction notes

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