Benzo(d)thiazol-2-amine → HCID 54695932, compound

HRID 1730552Notes

Reaction equation

HRID 1730552 reaction equation
CO[C:3]([C:5]1[N:6]([CH3:22])[S:7](=[O:21])(=[O:20])[C:8]2[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH:13]=[CH:12][C:9]=2[C:10]=1[OH:11])=[O:4].[NH2:23][C:24]1[S:25][C:26]2[CH:32]=[CH:31][CH:30]=[CH:29][C:27]=2[N:28]=1>C1(C)C(C)=CC=CC=1>[S:25]1[C:26]2[CH:32]=[CH:31][CH:30]=[CH:29][C:27]=2[N:28]=[C:24]1[NH:23][C:3]([C:5]1[N:6]([CH3:22])[S:7](=[O:21])(=[O:20])[C:8]2[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH:13]=[CH:12][C:9]=2[C:10]=1[OH:11])=[O:4]

Participants

4

Reactant 2

HCID 8706Benzo(d)thiazol-2-amineHCID 546906514-hydroxy-2-methyl-2H-naphtho[2,1-e]-1,2-thiazine-3-carboxylic acid methylester-1,1-dioxide

Product 1

HCID 54695932HCID 54695932, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

N-(2-Benzothiazolyl)-4-hydroxy-2-methyl-2H-naphtho[2,1-e]-1,2-thiazine-3-carboxamide-1,1-dioxide was prepared analogous to Example 22 from 4-hydroxy-2-methyl-2H-naphtho[2,1-e]-1,2-thiazine-3-carboxylic acid methylester-1,1-dioxide and 2-amino-benzothiazole. Yield: 70% of theory, m.p. 262° C (decomp.; from xylene).

Sources & evidence

ORD record
ord-e13963a371a34f40a63d2a1dd0ededb9
Source dataset
uspto-grants-1976_11
Patent number
US03992535

Reaction notes

Loading…