Potassium Carbonate → 2-(Dibenzo[b,d]furan-2-yloxy)-1-(p-tolyl)ethanone

HRID 1730639Notes

Reaction equation

HRID 1730639 reaction equation
[OH:1][C:2]1[CH:14]=[CH:13][C:5]2[O:6][C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=3[C:4]=2[CH:3]=1.[CH3:15][C:16]1[CH:25]=[CH:24][C:19]([C:20](=[O:23])[CH2:21]Cl)=[CH:18][CH:17]=1.C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[CH:3]1[C:4]2[C:8]3[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=3[O:6][C:5]=2[CH:13]=[CH:14][C:2]=1[O:1][CH2:21][C:20]([C:19]1[CH:24]=[CH:25][C:16]([CH3:15])=[CH:17][CH:18]=1)=[O:23]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 665872-DibenzofuranolHCID 2378052-Chloro-1-(4-methylphenyl)ethan-1-one

Product 1

HCID 214959752-(Dibenzo[b,d]furan-2-yloxy)-1-(p-tolyl)ethanone

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Following the procedure given in Example 13a 2-hydroxydibenzofuran was interacted with 4-methylphenacylchloride in the presence of anhydrous potassium carbonate in acetone to give ω-(2-dibenzofuranyloxy)-p-methylacetophenone. Following recrystallization from 2-ethoxyethanol, this compound melted at 162°-164° C.

Sources & evidence

ORD record
ord-ee1c8a2e2db44882b3f11907cf3e3fbd
Source dataset
uspto-grants-1976_11
Patent number
US03993645

Reaction notes

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