Water → HCID 53655940, compound

Participants

Reaction Steps

A solution of 11.5 gm (39.3 millimols) of (2'-fluoro-4-biphenylyl)-methyl-sulfinyl-acetic acid in 60 ml of dimethyl sulfoxide, was admixed with 8.2 gm of dry potassium carbonate and 8.4 gm of methyl iodide, and the mixture was stirred at room temperature for 3 hours. Thereafter, water was added, whereupon the reaction product crystallized out and was suction-filtered off, dried and recrystallized from carbon tetrachloride and isopropanol Yield: 3.8 gm (32% of theory); m.p. 79°-80° C

Provenance & Evidence