Pyridine → N-[4-Chloro-2-(2-chlorobenzoyl)phenyl]acetamide

HRID 1730761Notes

Reaction equation

HRID 1730761 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][C:3]=1[C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[Cl:12])=[O:5].[C:18](Cl)(=[O:20])[CH3:19].N1C=CC=CC=1>CCOCC>[Cl:12][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=1[C:4]([C:3]1[CH:13]=[C:14]([Cl:17])[CH:15]=[CH:16][C:2]=1[NH:1][C:18](=[O:20])[CH3:19])=[O:5]

Participants

5

Reactant 3

HCID 1049PyridineHCID 6367Acetyl chlorideHCID 180692-Amino-2',5-dichlorobenzophenone

Product 1

HCID 540625N-[4-Chloro-2-(2-chlorobenzoyl)phenyl]acetamide

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

In the manner given in Preparation 1, 2-amino-2',5-dichlorobenzophenone, acetyl chloride and pyridine were reacted in ether to give 2'-(o-chlorobenzoyl)-4'-chloroacetanilide.

Sources & evidence

ORD record
ord-b09f1c4151804eb2bcb085c35cddc259
Source dataset
uspto-grants-1976_11
Patent number
US03993660

Reaction notes

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