HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → Clonazolam
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | HCID 21496157 | HCID 21496157 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Clonazolam | HCID 12317881 | — |
Reaction Steps
In the manner given in Example 4, 5-nitro-2'-chloro-2-[3-(phthalimidomethyl)-5-methyl-4H-1,2,4-triazol-4-yl]benzophenone was heated in ethanol with hydrazine hydrate to give 8-nitro-1-methyl-6-(o-chlorophenyl)-4H-s-triazolo-[4,3-a][1,4]benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03993660 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-bfae0bc6f141443cb5853cbd487ee73a |
| Source note | uspto-grants-1976_11 |