Hydrazine hydrate (1:1) → HCID 21496151, compound

HRID 1730775Notes

Reaction equation

HRID 1730775 reaction equation
[CH:1]([NH:3][C:4]1[C:9]([C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[Cl:18])=O)=[C:8]([N:19]2[C:23]([CH2:24][C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)=[N:22][N:21]=[C:20]2[CH2:31][N:32]2C(=O)C3=CC=CC=C3C2=O)[CH:7]=[CH:6][CH:5]=1)=[O:2].O.NN>C(O)C>[CH2:24]([C:23]1[N:19]2[C:8]3[CH:7]=[CH:6][CH:5]=[C:4]([NH:3][CH:1]=[O:2])[C:9]=3[C:10]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=3[Cl:18])=[N:32][CH2:31][C:20]2=[N:21][N:22]=1)[C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 21496166HCID 21496166, compound

Product 1

HCID 21496151HCID 21496151, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In the manner given in Example 5, 6-formamido-2'-chloro-2-[3-(phthalimidomethyl)-5-benzyl-4H-1,2,4-triazol-4-yl]benzophenone was heated in ethanol with hydrazine hydrate to give 1-benzyl-7-formamido-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.

Sources & evidence

ORD record
ord-2d1ff73c204f459b8a7cd926dd50fac0
Source dataset
uspto-grants-1976_11
Patent number
US03993660

Reaction notes

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