反应详情

A solution of 15.9 g. (0.05 mol.) of α-phenylglycine, diphenylmethyl ester, and 9 g. (0.1 mol.) of ethylthioformate in 50 ml. of tetrahydrofuran is stirred overnight at room temperature. Then a stream of hydrogen sulfide is passed into the solution for 10 minutes, the reaction mixture is permitted to stand overnight, then concentrated and petroleum ether is added to the residue. 16.9 g. of α-[(thioxomethyl)amino]benzeneacetic acid, diphenylmethyl ester, crystallizes. The crude product is recrystallized from methanol, m.p. 129°-130°.

1. concentrationconcentrated
2. additionpetroleum ether is added to the residue
3. customof α-[(thioxomethyl)amino]benzeneacetic acid, diphenylmethyl ester, crystallizes
4. customThe crude product is recrystallized from methanol, m.p. 129°-130°