HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromopropane → 6-(Butylamino)-2-propyl[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromopropane | HCID 7840 | — |
| Reactant | 6-(Butylamino)[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one | HCID 21494309 | — |
| Product | 6-(Butylamino)-2-propyl[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one | HCID 21494318 | 86% |
Reaction Steps
By reacting the product of Example 3 with propyl bromide according to the procedure of Example 4, 6-n-butylamino-2-propyl-1,2,4-triazolo[4,3-b]pyridazin-3(2H)-one is obtained, yield 86%, m.p. 183°-185° (ethyl acetate with some drops of absolute ethanol). The hydrochloride is obtained by treatment with ethanolic HCl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03994898 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-9051f45b06ad4561a92b33a4f602c869 |
| Source note | uspto-grants-1976_11 |