Hydrogen Bromide → 4-(Pyridin-4-yl)aniline

HRID 1730908Notes

Reaction equation

HRID 1730908 reaction equation
C[N:2](C)[C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=2)=[CH:5][CH:4]=1.Cl.N1C=CC=CC=1.Br>>[NH2:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]2[CH:10]=[CH:11][N:12]=[CH:13][CH:14]=2)=[CH:7][CH:8]=1

Participants

4

Reactant 3

HCID 260Hydrogen BromideHCID 227783Pyridine, 4-(4-dimethylaminophenyl)-HCID 10176127Pyridinium chloride

Product 1

HCID 15126544-(Pyridin-4-yl)aniline

Procedure

In the process according to claim 1, the step which comprises reacting 4-(4-dimethylaminophenyl)pyridine with pyridine hydrochloride or hydrobromide at about 130°-260°C. to yield 4-(4-aminophenyl)pyridine.

Workup

  1. customat about 130°-260°C.

Sources & evidence

ORD record
ord-3256e5324522442087c6757e0ab4f138
Source dataset
uspto-grants-1976_11
Patent number
US03994903

Reaction notes

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