Hydrochloric Acid → HCID 131710539, compound

Participants

Reaction Steps

A solution of 8-[[3-(dimethylamino)propyl]thio]-3,4-dihydro-4-phenyl-2(1H)-quinolinone (5.0g) in 50 ml of chloroform is treated with 2.1 ml of 6.9N ethanolic hydrogen chloride and the resulting solution is slowly diluted to 200 ml with ether to yield 5.5g of a colorless solid, melting point 179°-181° C. After crystallization from 70 ml of acetonitrile, the product weighs 5.0g, melting point 181°-183° C.

Provenance & Evidence