Hydrochloric Acid → HCID 131710543, compound

HRID 1730918Notes

Reaction equation

HRID 1730918 reaction equation
[CH3:1][N:2]([CH3:23])[CH2:3][CH2:4][O:5][C:6]1[CH:7]=[C:8]2[C:13](=[CH:14][CH:15]=1)[NH:12][C:11](=[O:16])[CH2:10][CH:9]2[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.[ClH:24]>CO>[ClH:24].[CH3:1][N:2]([CH3:23])[CH2:3][CH2:4][O:5][C:6]1[CH:7]=[C:8]2[C:13](=[CH:14][CH:15]=1)[NH:12][C:11](=[O:16])[CH2:10][CH:9]2[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 214943326-[2-(Dimethylamino)ethoxy]-4-phenyl-3,4-dihydroquinolin-2(1H)-one

Product 1

HCID 131710543HCID 131710543, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of 6-[2-(dimethylamino)ethoxy]-3,4-dihydro-4-phenyl-2(1H)-quinolinone (13.2g) in 40 ml of methanol is treated with one equivalent of ethanolic hydrogen chloride to form 13.5g of crystals, melting point 240°-244° C. Crystallization from a solution of 100 ml of methanol and 1 ml of water gives 10.6g of product, melting point 242°-244° C.

Sources & evidence

ORD record
ord-d1e0026caeeb43aaac84d7bd2671b8f4
Source dataset
uspto-grants-1976_11
Patent number
US03994900

Reaction notes

Loading…