HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → 1-Phthalimidopropyl-3-phenyl-5-chloroindazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2-(3-Chloropropyl)-1H-isoindole-1,3(2H)-dione | HCID 245265 | — |
| Reactant | 5-Chloro-3-phenyl-1H-indazole | HCID 615118 | — |
| Product | 1-Phthalimidopropyl-3-phenyl-5-chloroindazole | HCID 68139474 | 62.2% |
Reaction Steps
By the procedure similar to that described in Example 24, 3-phenyl-5-chloroindazole (9.2 g), sodium hydride 50% pure (2.3 g) and phthalimidopropyl chloride (9.0 g) were treated to obtain 10.4 g of 1-phthalimidopropyl-3-phenyl-5-chloroindazole. Recrystallization from methanol gave a product having a melting point between 121°-122° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03994890 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-4a9d886ef31340c58290ae1b777dab7a |
| Source note | uspto-grants-1976_11 |