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HRID1730943

反应详情

EQUATION

反应方程式

HRID 1730943 的结构方程式

REACTANTS

反应物

3
结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：O=C1c2ccccc2C(=O)N1CCCCl
HCID245265

2-(3-Chloropropyl)-1H-isoindole-1,3(2H)-dione

C11H10ClNO2

结构：Clc1ccc2[nH]nc(-c3ccccc3)c2c1
HCID615118

5-Chloro-3-phenyl-1H-indazole

C13H9ClN2

PRODUCTS

生成物

1
结构：CCC(c1c(Cl)ccc2[nH]nc(-c3ccccc3)c12)N1C(=O)c2ccccc2C1=O
HCID68139474

未命名化合物

收率 62.2%

PROCEDURE

实验过程

By the procedure similar to that described in Example 24, 3-phenyl-5-chloroindazole (9.2 g), sodium hydride 50% pure (2.3 g) and phthalimidopropyl chloride (9.0 g) were treated to obtain 10.4 g of 1-phthalimidopropyl-3-phenyl-5-chloroindazole. Recrystallization from methanol gave a product having a melting point between 121°-122° C.

WORKUP

后处理

  1. additionwere treated