Hydrazine hydrate (1:1) → HCID 68141327, compound

HRID 1730948Notes

Reaction equation

HRID 1730948 reaction equation
C1(=O)[N:5]([CH:6]([C:9]2[C:17]([CH3:18])=[CH:16][CH:15]=[C:14]3[C:10]=2[C:11]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[N:12][NH:13]3)[CH2:7][CH3:8])C(=O)C2=CC=CC=C12.O.NN>>[NH2:5][CH:6]([C:9]1[C:17]([CH3:18])=[CH:16][CH:15]=[C:14]2[C:10]=1[C:11]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)=[N:12][NH:13]2)[CH2:7][CH3:8]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 68139467HCID 68139467, compound

Product 1

HCID 68141327HCID 68141327, compoundYield 92.4%

Procedure

By the procedure similar to that described in Example 33, 1-phthalimidopropyl-3-phenyl-5-methylindazole (5.0 g) and hydrazine hydrate (1.5 g) were treated to obtain 3.1 g of 1-aminopropyl-3-phenyl-5-methylindazole as an oily product. The product was converted by a conventional way to its hydrochloride having a melting point between 161°-163° C.

Workup

  1. additionwere treated

Sources & evidence

ORD record
ord-e0d166435f0044d0af82482bc19d6427
Source dataset
uspto-grants-1976_11
Patent number
US03994890

Reaction notes

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