Isopropyl chloroformate → HCID 21494443, compound

Participants

Reaction Steps

17.6 parts of 3-benzyl-5-hydroxy-1,2,4-oxadiazole, 6.9 parts of potassium carbonate and 12.3 parts of isopropyl chloroformate are heated for 5 hours at 60° C. After the mixture has cooled, the precipitated potassium chloride is removed by suction filtration and the filtrate concentrated. The residue is recrystallized from n-propanol. There is obtained 15.5 parts (59% of theory) of the desired product; m.p.: 80° C.

Provenance & Evidence