Ethylenediamine → HCID 388688, compound

HRID 1730983Notes

Reaction equation

HRID 1730983 reaction equation
[F:1][C:2]1[CH:18]=[CH:17][C:5]([C:6]([C:8]2[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=2[C:10]([OH:12])=O)=O)=[CH:4][CH:3]=1.[CH2:19]([NH2:22])[CH2:20][NH2:21]>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]23[NH:22][CH2:19][CH2:20][N:21]2[C:10](=[O:12])[C:9]2[C:8]3=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:17][CH:18]=1

Participants

3

Reactant 2

HCID 3301EthylenediamineHCID 820992-(4-Fluorobenzoyl)benzoic acid

Product 1

HCID 388688HCID 388688, compound

Procedure

Condense o-(p-fluorobenzoyl)benzoic acid with ethylenediamine by the procedure of Example 1 to obtain 9b-(p-fluorophenyl)-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one, reduce with lithium aluminum hydride and treat with hydrogen chloride as described in Example 1 to obtain 1-(p-fluorophenyl)-1,2,3,4,5,6-hexahydro-2,5-benzodiazocine, dihydrochloride, m.p. 303° C. (dec.).

Sources & evidence

ORD record
ord-13e1cc1392e743e5aedc039e5b9f42b1
Source dataset
uspto-grants-1976_11
Patent number
US03994920

Reaction notes

Loading…