Bicarbonate Ion → N-(2-(6-(3-Amino-2-oxo-1,2-dihydroquinoxalin-5-yloxy)pyrimidin-4-yl)-5-(trifluoromethyl)phenyl)-1-isobutylpiperidine-2-carboxamide
Reaction equation
[C:44](=[O:45])([O-:46])[O-:47].[Cl:14][c:15]1[cH:16][c:17](-[c:21]2[c:22]([NH:31][C:32](=[O:33])[CH:34]3[N:35]([CH2:40][CH:41]([CH3:42])[CH3:43])[CH2:36][CH2:37][CH2:38][CH2:39]3)[cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:26]2)[n:18][cH:19][n:20]1.[Cs+:48].[Cs+:49].[NH2:1][c:2]1[c:3](=[O:13])[nH:4][c:5]2[cH:6][cH:7][cH:8][c:9]([OH:12])[c:10]2[n:11]1.[Na+:59].[O-:55][C:56]([OH:57])=[O:58].[O:50]=[CH:51][N:52]([CH3:53])[CH3:54]>>[NH2:1][c:2]1[c:3](=[O:13])[nH:4][c:5]2[cH:6][cH:7][cH:8][c:9]([O:12][c:15]3[cH:16][c:17](-[c:21]4[c:22]([NH:31][C:32](=[O:33])[CH:34]5[N:35]([CH2:40][CH:41]([CH3:42])[CH3:43])[CH2:36][CH2:37][CH2:38][CH2:39]5)[cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:26]4)[n:18][cH:19][n:20]3)[c:10]2[n:11]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-0f79168bd97c450e943bdd243481538a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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