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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1731077Generated: November 1, 2026

Formaldehyde → HCID 21494813, compound

https://huagongshe.com/reaction/1731077

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantClonazolamHCID 12317881—
SolventO-XyleneHCID 7237—
ProductHCID 21494813HCID 21494813—

Reaction Steps

In the manner given in Example 1, 8-nitro-6-(o-chlorophenyl)-1-methyl-4H-s-triazolo[4,3-a][1,4]-benzodiazepine in xylene was heated in an oil bath with repeated additions of portions of paraformaldehyde to give 8-nitro-1-(2-hydroxyethyl)-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03994941
Source datasetuspto-grants-1976_11
ORD IDord-7d011f72d7ba4b2b99aefb332324281d
Source noteuspto-grants-1976_11