HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → HCID 21494826, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | HCID 21494847 | HCID 21494847 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | HCID 21494826 | HCID 21494826 | — |
Reaction Steps
In the manner given in Example 1, 8-trifluoromethyl-6-(o-chlorophenyl)-1-methyl-4H-s-triazolo[4,3-a][1,4]-benzodiazepine in xylene is heated with excess paraformaldehyde in a sealed, glass-lined vessel at 155°-160° C. to give 8-trifluoromethyl-1-(2-hydroxyethyl)-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03994941 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-2c734a1e2ba1413ca392fda2ef7568ac |
| Source note | uspto-grants-1976_11 |