Oxalyl chloride → HCID 21495612, compound

HRID 1731159Notes

Reaction equation

HRID 1731159 reaction equation
[C:1]([C:9]1[CH:10]=[C:11]([CH2:15][CH2:16][C:17]([OH:19])=O)[CH:12]=[CH:13][CH:14]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(Cl)(=O)C([Cl:23])=O>>[C:1]([C:9]1[CH:10]=[C:11]([CH2:15][CH2:16][C:17]([Cl:23])=[O:19])[CH:12]=[CH:13][CH:14]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 65578Oxalyl chlorideHCID 15727607HCID 15727607, compound

Product 1

HCID 21495612HCID 21495612, compound

Procedure

A mixture of 10 g of 3-(m-benzoyl-phenyl)-propionic acid and 50 ml of oxalyl chloride was stirred for 4 hours at room temperature and the excess oxalyl chloride was removed under reduced pressure. The resulting oil was taken up twice in 50 ml of benzene and evaporated to dryness under reduced pressure to obtain 10.7 g of 3-(m-benzoyl-phenyl)-propionyl chloride identical to Example I.

Workup

  1. customthe excess oxalyl chloride was removed under reduced pressure
  2. customevaporated to dryness under reduced pressure

Sources & evidence

ORD record
ord-2afae40c33cc417196e2e18d351f5e7d
Source dataset
uspto-grants-1976_11
Patent number
US03995056

Reaction notes

Loading…