2-Methyl-3-nitrobenzoic acid → 2-Methyl-3-nitrobenzoyl chloride

HRID 1731160Notes

Reaction equation

HRID 1731160 reaction equation
[CH3:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4](O)=[O:5].S(Cl)([Cl:16])=O>>[CH3:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([Cl:16])=[O:5]

Participants

3

Reactant 2

HCID 160962-Methyl-3-nitrobenzoic acidHCID 24386Thionyl Chloride

Product 1

HCID 121948722-Methyl-3-nitrobenzoyl chloride

Procedure

100 g of 2-methyl-3-nitro-benzoic acid and 500 ml of thionyl chloride were refluxed for 15 hours and the mixture was then evaporated to dryness under reduced pressure to obtain 110 g of 2-methyl-3-nitro-benzoyl chloride which was used as in the synthesis.

Workup

  1. customthe mixture was then evaporated to dryness under reduced pressure

Sources & evidence

ORD record
ord-054a6a5718954577aa911558ed8987dc
Source dataset
uspto-grants-1976_11
Patent number
US03995056

Reaction notes

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