Hydrazine → HCID 178448003, compound

HRID 1731277Notes

Reaction equation

HRID 1731277 reaction equation
[CH2:1]([C@H:4]1[CH2:9][CH2:8][C@H:7]([C@H:10]2[CH2:15][CH2:14][C@H:13]([C:16]3[CH:21]=[CH:20][C:19]([C:22](=O)[CH3:23])=[CH:18][CH:17]=3)[CH2:12][CH2:11]2)[CH2:6][CH2:5]1)[CH2:2][CH3:3].[OH-].[K+].NN>C(O)COCCO>[CH2:22]([C:19]1[CH:20]=[CH:21][C:16]([C@H:13]2[CH2:14][CH2:15][C@H:10]([C@H:7]3[CH2:8][CH2:9][C@H:4]([CH2:1][CH2:2][CH3:3])[CH2:5][CH2:6]3)[CH2:11][CH2:12]2)=[CH:17][CH:18]=1)[CH3:23]

Participants

5

Reactant 3

HCID 9321HydrazineHCID 14797Potassium HydroxideHCID 178448005HCID 178448005, compound

Product 1

HCID 178448003HCID 178448003, compound

Reagents, catalysts & solvents 1

HCID 8117Diethylene GlycolSolvent

Procedure

A mixture of 32.6 g of p-(trans-4-(trans-4-propylcyclohexyl)-cyclohexyl)-acetophenone, 15 g of KOH, 25 ml of 85% hydrazine and 250 ml of diethylene glycol is warmed to 100° for 1 hour. The temperature is increased slowly until the hydrazone formed decomposes, and is boiled for another 4 hours, cooled and worked up in the customary manner to give trans-1-p-ethylphenyl-4-(trans-4-propylcyclohexyl)-cyclohexane.

Workup

  1. temperatureis warmed to 100° for 1 hour
  2. temperaturecooled

Sources & evidence

ORD record
ord-511c453ec3c24fe48ca6d44c16c972fc
Source dataset
uspto-grants-1986_11
Patent number
US04620938

Reaction notes

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