HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → Ethyl 3-oxo-1-(phenylmethyl)-4-piperidinecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 20228749 | HCID 20228749 | — |
| Product | Ethyl 3-oxo-1-(phenylmethyl)-4-piperidinecarboxylate | HCID 419705 | — |
Reaction Steps
The anion of ethyl 3-oxo-1-phenylmethyl-4-piperidinecarboxylate is prepared according to Example 1(a) above, from 30.7 g (0.1 mole) of 4-[(2-ethoxy-2-oxoethyl)(phenylmethyl)amino]butanoate in 700 ml of toluene and 5 g (0.1 mole) of 50% strength sodium hydride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04621087 |
| Source dataset | uspto-grants-1986_11 |
| ORD ID | ord-4c6a48ec9acb4711ac40246b75796c04 |
| Source note | uspto-grants-1986_11 |