2-Amino-4-methylpyridine → HCID 70414051, compound

HRID 1731333Notes

Reaction equation

HRID 1731333 reaction equation
Br[CH:2]([CH3:17])[C:3]([C:5]1[CH:6]=[CH:7][C:8]2[S:13][CH2:12][C:11](=[O:14])[N:10]([CH3:15])[C:9]=2[CH:16]=1)=O.[NH2:18][C:19]1[CH:24]=[C:23]([CH3:25])[CH:22]=[CH:21][N:20]=1>>[CH3:17][C:2]1[N:20]2[CH:21]=[CH:22][C:23]([CH3:25])=[CH:24][C:19]2=[N:18][C:3]=1[C:5]1[CH:6]=[CH:7][C:8]2[S:13][CH2:12][C:11](=[O:14])[N:10]([CH3:15])[C:9]=2[CH:16]=1

Participants

3

Reactant 2

HCID 15332-Amino-4-methylpyridineHCID 20228672HCID 20228672, compound

Product 1

HCID 70414051HCID 70414051, compoundYield 58.8%

Procedure

6-(3,7-Dimethylimidazo[1,2-a]pyridin-2-yl)-4-methyl-3-oxo-3,4-dihyro-2H-1,4-benzothiazine (1.9 g) was prepared in the substantially same manner as that of Example 4 from 6-(2-bromopropionyl)-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazine (3.14 g) and 2-amino-4-methyl-pyridine (3.24 g).

Sources & evidence

ORD record
ord-670bd94881b742bfb4bd8554093aaf15
Source dataset
uspto-grants-1986_11
Patent number
US04621084

Reaction notes

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