Hydroxyamine hydrochloride → HCID 13732599, compound

Participants

Reaction Steps

1-Ethyl-4-hydroxy-5-(4-methylbenzoyl)-1H-pyrazolo[3,4-b]pyridine (1.45 g) was refluxed overnight in 20 ml of pyridine containing 3.0 g of hydroxylamine hydrochloride. The pyridine was then evaporated and the residue triturated with 5% hydrochloric acid and then washed with methanol. In this manner 1.26 g of product was obtained, mp 173°-175° C. An analytical sample was recrystallized from dichloromethane/hexane and the melting point was unchanged.

Provenance & Evidence