4-Iodobenzenesulfonyl chloride → 2,4-Dimethyl-1-[3-(4-iodobenzenesulphonamido)propyl]pyrrolidine

Participants

Reaction Steps

A solution of 2,4-dimethyl-1-(3-aminopropyl)pyrrolidine (4.7 g, 0.03 mol) in benzene (20 ml) was added dropwise to a solution of 4-iodobenzenesulphonylchloride (9.1 g, 0.03 mol) benzene (80 ml). After stirring the resulting mixture for six hours at room temperature, the reaction product separated as an oil. The reaction mixture was evaporated, and the residue was dissolved in absolute alcohol (800 ml) and boiled with charcoal.

Provenance & Evidence