HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-1-(3-chlorophenyl)ethan-1-ol → HCID 20227982, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-1-(3-chlorophenyl)ethan-1-ol | HCID 3751601 | — |
| Reactant | HCID 18628161 | HCID 18628161 | — |
| Product | HCID 20227982 | HCID 20227982 | — |
Reaction Steps
N-[2-(3,5-difluoro-4-methoxyphenyl)-1-methylethyl]-2-hydroxy-2-(3-chlorophenyl)ethanamine hydrochloride, m.p. 120°-140° C. was prepared from 1-(3,5-difluoro-4-methoxyphenyl)propan-2-one (500 mg) and 2-hydroxy-2-(3-chlorophenyl)ethanamine (430 mg) as a 44:56 mixture of diastereoisomers, by an analogous procedure to that described in Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04622342 |
| Source dataset | uspto-grants-1986_11 |
| ORD ID | ord-5f5d363672fb4183842459756cd28ab8 |
| Source note | uspto-grants-1986_11 |