Potassium Hydroxide → HCID 13746694, compound

Participants

Reaction Steps

Methyl 2,3,10,11-tetrahydro-1H-benzo[b]indeno[5,6-f]thiepin-7-carboxylate 5-oxide (2.00 g; 6.13 mmole) was added to a solution of 85% potassium hydroxide (808 mg; 12.26 mmole) in a mixture of water (8 ml) and ethanol (40 ml) at room temperature. After 1 hour, the solution was filtered, evaporated to 15 ml and acidified to pH 2 with hydrochloric acid. The product was collected, washed with water and dried (finally at 105° C./0.005 Torr) to yield 1.55 g (81%) with a m.p. 290°-294° dec.

Provenance & Evidence