Hydrazine hydrate (1:1) → HCID 13385673, compound

HRID 1731909Notes

Reaction equation

HRID 1731909 reaction equation
Cl[C:2]1[C:11]([O:12][CH3:13])=[N:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:14])[CH:8]=2)[N:3]=1.O.[NH2:16][NH2:17]>C(O)C>[Cl:14][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]=[C:2]([NH:16][NH2:17])[C:11]([O:12][CH3:13])=[N:10]2

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 13385672HCID 13385672, compound

Product 1

HCID 13385673HCID 13385673, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 4.9 g. (0.02 mole) of 2,6-dichloro-3-methoxyquinoxaline and 2.7 g. (0.053 mole) of hydrazine hydrate (2.6 ml.) in 75 ml. of ethanol was stirred at room temperature overnight (i.e., at ca. 20° C. for approximately 16 hours). Upon completion of this step, the resulting mixture was filtered and the recovered precipitate was washed with ethanol to ultimately afford 4.4 g. (98%) of pure 6-chloro-2-hydrazino-3-methoxyquinoxaline, m.p. 175°-179° C. (decomp.). Mass Spectrum: m/e, 224 (P); m/e, 226 (P+2).

Workup

  1. additionA mixture of 4.9 g
  2. filtrationUpon completion of this step, the resulting mixture was filtered
  3. washthe recovered precipitate was washed with ethanol to ultimately afford 4.4 g

Sources & evidence

ORD record
ord-d3ccd864e4384cc68ed6e5a95274db6f
Source dataset
uspto-grants-1986_11
Patent number
US04623725

Reaction notes

Loading…