Diethylamine → HCID 13385715, compound

HRID 1731942Notes

Reaction equation

HRID 1731942 reaction equation
Cl[C:2]1[C:3]2[N:4]([C:12]([CH2:15][CH3:16])=[N:13][N:14]=2)[C:5]2[C:10]([N:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.Cl[C:18]1[C:19]2[N:20](C=NN=2)[C:21]2C(N=1)=CC=C[CH:22]=2.C(NCC)C.C(NCCC)CC>>[CH2:19]([N:20]([CH2:21][CH3:22])[C:2]1[C:3]2[N:4]([C:12]([CH2:15][CH3:16])=[N:13][N:14]=2)[C:5]2[C:10]([N:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH3:18]

Participants

5

Reactant 4

HCID 8021DiethylamineHCID 8902DipropylamineHCID 11261184-Chloro[1,2,4]triazolo[4,3-a]quinoxalineHCID 133857064-Chloro-1-ethyl-[1,2,4]triazolo[4,3-a]quinoxaline

Product 1

HCID 13385715HCID 13385715, compoundYield 69%

Procedure

This compound was prepared by the method of Example 11, utilizing 4-chloro-1-ethyl-[1,2,4]triazolo[4,3-a]quinoxaline (the product of Example 4) as starting material in place of 4-chloro-[1,2,4]triazolo[4,3-a]quinoxaline (the product of Example 2) and diethylamine as reagent in place of di-n-propylamine. The crude product was recrystallized from cyclohexane to afford 3.54 g. (69% yield) of pure 4-diethylamino-1-ethyl-[1,2,4]triazolo[4,3-a]quinoxaline as a white solid (m.p. 98°-100° C.).

Workup

  1. customThe crude product was recrystallized from cyclohexane
  2. customto afford 3.54 g

Sources & evidence

ORD record
ord-8c5afc19b36442cb9fc4bb1408c560ec
Source dataset
uspto-grants-1986_11
Patent number
US04623725

Reaction notes

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