Hydrochloric Acid → HCID 20226448, compound

HRID 1732032Notes

Reaction equation

HRID 1732032 reaction equation
[NH2:1][C:2]1[C:10]([Cl:11])=[CH:9][C:5]([C:6]([OH:8])=O)=[C:4]([O:12][CH3:13])[CH:3]=1.C(OC([Cl:19])=O)C.[NH2:20][CH:21]1[CH2:25][N:24]([CH:26]([CH3:28])[CH3:27])[N:23]([CH3:29])[CH2:22]1.Cl>>[ClH:11].[ClH:19].[NH2:1][C:2]1[C:10]([Cl:11])=[CH:9][C:5]([C:6]([NH:20][CH:21]2[CH2:25][N:24]([CH:26]([CH3:28])[CH3:27])[N:23]([CH3:29])[CH2:22]2)=[O:8])=[C:4]([O:12][CH3:13])[CH:3]=1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 10928Ethyl chloroformateHCID 816264-Amino-5-chloro-2-methoxybenzoic acidHCID 20226438HCID 20226438, compound

Product 1

HCID 20226448HCID 20226448, compound

Procedure

The title compound was prepared as described in Example 11 of U.S. Pat. No. 4,207,327 from 4-amino-5-chloro-2-methoxybenzoic acid, ethylchlorocarbonate and 4-amino-1-isopropyl-2-methylpyrazolidine and hydrogen chloride, m.p. 182°-186° C.

Sources & evidence

ORD record
ord-8f64c4dc0c814fb2b0e1241e4bf9b39b
Source dataset
uspto-grants-1986_11
Patent number
US04624961

Reaction notes

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