HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-Chloropropiophenone → 2-Bromo-1-(4-chlorophenyl)propan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-Chloropropiophenone | HCID 22697 | — |
| Reactant | Bromine | HCID 24408 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 2-Bromo-1-(4-chlorophenyl)propan-1-one | HCID 3788219 | — |
Reaction Steps
4-Chloropropiophenone (33.6 g.) was dissolved in anhydrous diethyl ether (50 ml.), stirred and cooled in an ice bath while bromine (32 g.) was added dropwise over 30 minutes. The solid which formed was filtered off, washed with water and air-dried to give 2-bromo-4'-chloropropiophenone, m.p. 77°-79°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04625036 |
| Source dataset | uspto-grants-1986_11 |
| ORD ID | ord-d0b1890de4d1444cb92880577ea74d94 |
| Source note | uspto-grants-1986_11 |