Potassium Permanganate → HCID 178519623, compound

Participants

Reaction Steps

3-(4-Fluorobenzyl)-1,2,4-triazole (9 g.) and potassium permanganate (13.5 g.) were heated in water at 80° for 1 hour. The reaction mixture was filtered, and the residue was washed twice each with water and chloroform. The combined filtrate and washings were adjusted to pH 3 and filtered. The solid residue was dissolved, as far as possible, in hot methanol, the solution was filtered and evaporated to dryness to give 3-(4-fluorobenzoyl)-1,2,4-triazole as a cream-colored solid, m.p. 225°-230°.

Provenance & Evidence