HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → N-(3-dimethylaminopropyl)-3-methoxypropionamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | N,N-Dimethyl-1,3-propanediamine | HCID 7993 | — |
| Reactant | 3-Methoxypropanamide | HCID 5252481 | — |
| Product | N-(3-dimethylaminopropyl)-3-methoxypropionamide | HCID 3097421 | — |
Reaction Steps
103.1 g (1.0 mole) of 3-methoxypropionamide are heated with 107.3 g (1.05 mole) of 3-dimethylaminopropylamine for 6 hours in a temperature range of 145°-170° C. until the evolution of ammonia is complete. In the subsequent distillation in a high vacuum 176 g (0.93 mole=93.5% of the theoretical yield) of a colorless liquid are obtained having Bp0.1 of 97°-99° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04237067 |
| Source dataset | uspto-grants-1980_12 |
| ORD ID | ord-b0e444c009db42a7915cf921cba49448 |
| Source note | uspto-grants-1980_12 |