2-Aminothiazole → HCID 57076477, compound

Participants

Reaction Steps

The procedure is as in Example 22, except that 5 g of 2-aminothiazole are reacted with 11.3 g of acetylene dicarboxylic acid di-n-butyl ester in presence of 50 ml of absolute ethanol. 7H-thiazolo-[3,2-a]-pyrimidin-7-one-5-carboxylic acid n-butyl ester melting at 142°-144° C. is thus obtained in a yield of 8.1 g (64.3% of the theoretical).

Provenance & Evidence