L 636499 → L 640035

HRID 1732356Notes

Reaction equation

HRID 1732356 reaction equation
[CH:1]1[C:11]2[CH:10]=[CH:9][C:8]3[CH:12]=[CH:13][CH:14]=[CH:15][C:7]=3[S:6](=[O:17])(=[O:16])[C:5]=2[CH:4]=[C:3]([C:18](O)=[O:19])[CH:2]=1.B#B>O1CCCC1.O>[OH:19][CH2:18][C:3]1[CH:2]=[CH:1][C:11]2[CH:10]=[CH:9][C:8]3[CH:12]=[CH:13][CH:14]=[CH:15][C:7]=3[S:6](=[O:17])(=[O:16])[C:5]=2[CH:4]=1

Participants

5

Reactant 2

HCID 130562L 636499HCID 6328200Diboron

Product 1

HCID 127538L 640035

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 8028TetrahydrofuranSolvent2×

Procedure

Mix 2.8 gm. of dibenzo[b,f]thiepin-3-carboxylic acid-5,5-dioxide, 50 ml. of tetrahydrofuran, and 30 ml. of 1 N diborane in tetrahydrofuran. Stir at room temperature for 1 hour. Dilute the reaction mixture with water, and extract into ether. Evaporate the ether extract to dryness. Stir the residue in ether, and filter to obtain the title product (m.p., 156°-158° C.).

Workup

  1. additionMix 2.8 gm
  2. extractionextract into ether
  3. customEvaporate the ether
  4. extractionextract to dryness
  5. stirringStir the residue in ether
  6. filtrationfilter

Sources & evidence

ORD record
ord-40c68a6c027440229da57a178d23caa2
Source dataset
uspto-grants-1980_12
Patent number
US04237160

Reaction notes

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