HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Peroxide → HCID 20304863, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | Piperazine, 1-(8-chloro-10,11-dihydro-2,3-dimethoxydibenzo(b,f)thiepin-10-yl)-4-methyl-, dimethanesulfonate | HCID 3045598 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 20304863 | HCID 20304863 | — |
Reaction Steps
A solution of 8-chloro-2,3-dimethoxy-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepine dimethanesulfonate (8.5 g) (see Example 4) in water (50 ml) was treated with 30% hydrogen peroxide (16 ml) and the mixture allowed to stand for 20 hours at room temperature. Addition of ammonium hydroxide liberated the base which was extracted with benzene. The extract affords an oily residue which crystallized from a mixture of benzene-light petroleum, m.p. 178°-179° C., yield 3.70 g of the desired base.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04238611 |
| Source dataset | uspto-grants-1980_12 |
| ORD ID | ord-9c83e70dd57540d79a1cb5be257eb61e |
| Source note | uspto-grants-1980_12 |