Hydrazine hydrate (1:1) → HCID 53714843, compound

HRID 1732791Notes

Reaction equation

HRID 1732791 reaction equation
[O:1]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][C:21]([O:23]C)=O)[C@@H:2]1[O:10][C@H:9]([CH2:11][OH:12])[C@H:7]([OH:8])[C@H:5]([OH:6])[C@H:3]1[OH:4].O.[NH2:26][NH2:27]>C(O)C>[O:1]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][C:21]([NH:26][NH2:27])=[O:23])[C@@H:2]1[O:10][C@H:9]([CH2:11][OH:12])[C@H:7]([OH:8])[C@H:5]([OH:6])[C@H:3]1[OH:4]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 5326972HCID 5326972, compound

Product 1

HCID 53714843HCID 53714843, compoundYield 92%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Compoud 1 (1 g) was dissolved in a mixture of ethanol (5 ml) and 85% hydrazine hydrate (2 ml). After 24 h the solvent was evaporated and residual traces of hydrazine removed by co-evaporation with toluene to give 8-hydrazinocarbonyloctyl β-D-galactopyranoside as a white solid which was recrystallized from ethanol, mp 194°, [α]D18 -2.16° (c 1.1, water), 92% yield.

Workup

  1. customAfter 24 h the solvent was evaporated
  2. customresidual traces of hydrazine removed by co-evaporation with toluene

Sources & evidence

ORD record
ord-fa3bf1c61d4a4c33922026d940ddd1b5
Source dataset
uspto-grants-1980_12
Patent number
US04238473

Reaction notes

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