Propionitrile → 15049-86-2

Participants

Reaction Steps

Into a reactor like the above was charged 261 g phosphorous acid. 44.3 g propionitrile was introduced slowly for 70 minutes at 135°-143° C. into the agitated phosphorous acid. The reactant mixture was held for additional 10 hours at 150°-155° C. The 1-aminopropane-1, 1-diphosphonic acid produced was isolated from the reaction mixture in the manner described in Example 1.

Provenance & Evidence