HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 825289, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 2-Thiophenecarbonyl chloride | HCID 78928 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 825289 | HCID 825289 | — |
Reaction Steps
Pyrrolidine (47 ml) was added to 2-thiophene carbonyl chloride (40 g) in toluene below 10°. After 11/2 hr, water was added. The product was extracted with ethyl acetate, crystallised from toluene and recrystallised from light petroleum (b.p. 60°-80°)/ethyl acetate to give white crystals (40 g) m.p. 66°-68°; TLC silica/ethyl acetate Rf 0.5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04239769 |
| Source dataset | uspto-grants-1980_12 |
| ORD ID | ord-31a5f175c9fe4340935617abafbacddc |
| Source note | uspto-grants-1980_12 |