反应详情

A suspension of N-nitrocarbamimidothioic acid methyl ester (1.05 g) and 2-[[[5-(N,N-dimethylaminomethyl)2-thienyl]methyl]thio]ethanamine (1.6 g) in ethanol (10 ml) was heated at 45° for 10 min. The resultant solid was recrystallised from ethyl acetate to give the title compound as white crystals (1.15 g) m.p. 118°-118.5°. TLC silica/methanol, Rf 0.40.

1. temperaturewas heated at 45° for 10 min
2. customThe resultant solid was recrystallised from ethyl acetate