HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(5-Dimethylaminomethyl-2-thienylmethylthio)ethylamine → HCID 178483235, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(5-Dimethylaminomethyl-2-thienylmethylthio)ethylamine | HCID 12913951 | — |
| Reactant | N-Nitro-S-methylisothiourea | HCID 135927615 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178483235 | HCID 178483235 | 52.2% |
Reaction Steps
A suspension of N-nitrocarbamimidothioic acid methyl ester (1.05 g) and 2-[[[5-(N,N-dimethylaminomethyl)2-thienyl]methyl]thio]ethanamine (1.6 g) in ethanol (10 ml) was heated at 45° for 10 min. The resultant solid was recrystallised from ethyl acetate to give the title compound as white crystals (1.15 g) m.p. 118°-118.5°. TLC silica/methanol, Rf 0.40.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04239769 |
| Source dataset | uspto-grants-1980_12 |
| ORD ID | ord-8475794d50e74af9a352185406f23790 |
| Source note | uspto-grants-1980_12 |