Sulfuryl chloride → HCID 12593650, 화합물

HRID 1732932노트

반응식

HRID 1732932 반응식
[Cl:1][C:2]1[CH:15]=[CH:14][CH:13]=[C:12]([Cl:16])[C:3]=1[NH:4][CH:5]1[C:9]([C:10]#[N:11])=[CH:8][S:7][CH2:6]1.S(Cl)(Cl)(=O)=O>C(Cl)Cl>[Cl:1][C:2]1[CH:15]=[CH:14][CH:13]=[C:12]([Cl:16])[C:3]=1[NH:4][C:5]1[C:9]([C:10]#[N:11])=[CH:8][S:7][CH:6]=1

참가 물질

4

반응물 2

HCID 24648Sulfuryl chlorideHCID 20300151HCID 20300151, 화합물

생성물 1

HCID 12593650HCID 12593650, 화합물수율 75%

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

실험 절차

A solution of 0.27 part of 3-(2',6'-dichloro-anilino)-4-cyanodihydrothiophene in 15 parts by volume of dry methylene chloride is added, in the course of 30 minutes, to a solution of 0.12 part by volume of sulfuryl chloride in 15 parts by volume of dry methylene chloride at 0° C. The end product is isolated from the reaction mixture by the method described in Example 1c. 0.20 part (75% of theory) of 3-(2',6'-dichloroanilino)-4-cyanothiophene of melting point 105°-108° C. are obtained.

후처리

  1. customThe end product is isolated from the reaction mixture by the method

출처 및 근거

ORD 기록
ord-7d57f021100848d095748f5203d033e9
출처 데이터셋
uspto-grants-1980_12
특허 번호
US04239897

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