HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 20302326, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | HCID 20302923 | HCID 20302923 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 20302326 | HCID 20302326 | — |
Reaction Steps
30.1 g of 3-acetoxy-3-(4'-fluoro-4-biphenylyl)-1-butylamine [obtainable from 3-bromo-3-(4'-fluoro-4-biphenylyl)-1-butylamine and potassium acetate] are boiled for 2 hours with 20 g of KOH in 500 ml of methanol, and the mixture is worked up with water and chloroform to give 3-(4'-fluoro-4-biphenylyl)-3-hydroxybutylamine, m.p. 144°-146°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04239759 |
| Source dataset | uspto-grants-1980_12 |
| ORD ID | ord-4bb78df97928415c933e00a5298bc87c |
| Source note | uspto-grants-1980_12 |