1,5-Dibromopentane → HCID 70596633, compound

HRID 1733059Notes

Reaction equation

HRID 1733059 reaction equation
[C:1]1([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH:7]([CH3:11])[CH2:8][CH2:9][NH2:10].C(=O)([O-])[O-].[K+].[K+].Br[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]Br>C(O)CCC>[N:10]1([CH2:9][CH2:8][CH:7]([C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][C:1]=2[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH3:11])[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1

Participants

5

Reactant 3

HCID 81001,5-DibromopentaneHCID 11430Potassium CarbonateHCID 70595812HCID 70595812, compound

Product 1

HCID 70596633HCID 70596633, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

A mixture of 2.25 g of 3-p-biphenylyl-butylamine, 1.38 g of potassium carbonate, 2.53 g of 1,5-dibromopentane and 15 ml of n-butanol is boiled for 24 hours, while stirring. The mixture is filtered and the filtrate is evaporated and worked up in the customary manner to give 1-piperidino-3-p-biphenylylbutane.

Workup

  1. filtrationThe mixture is filtered
  2. customthe filtrate is evaporated

Sources & evidence

ORD record
ord-f395895208fb4e24a45d6d8ff3ad2970
Source dataset
uspto-grants-1980_12
Patent number
US04239759

Reaction notes

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