5-Aminopentan-1-ol → HCID 20300316, compound

HRID 1733126Notes

Reaction equation

HRID 1733126 reaction equation
[N+:1]([CH:4]=[C:5](SC)SC)([O-:3])=[O:2].N[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][OH:16]>C(O)C>[OH:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][C:5]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][OH:16])=[CH:4][N+:1]([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 756345-Aminopentan-1-olHCID 836231,1-Bis(methylthio)-2-nitroethylene

Product 1

HCID 20300316HCID 20300316, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Heating 1-nitro-2,2-bis(methylthio)ethylene with an excess of 5-aminopentan-1-ol in ethanol gives 1,1-bis(5-hydroxypentyl)-2-nitroethylene, which may be treated with p-toluenesulphonyl chloride in pyridine and the product heated with thiourea in acetone to give 1,1-bis(5-(S-isothioureido)pentyl)-2-nitroethylene.

Sources & evidence

ORD record
ord-d05e0bb1ed984afc94e6fe749e3d6fc2
Source dataset
uspto-grants-1980_12
Patent number
USRE030457

Reaction notes

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