3-Methoxypropylamine → HCID 54230429, compound

HRID 1733211Notes

Reaction equation

O=[CH:2][C@H:3]([C@@H:5]([C@@H:7]([CH2:9][OH:10])[OH:8])[OH:6])[OH:4].[CH3:11][O:12][CH2:13][CH2:14][CH2:15][NH2:16].[Cl:17][CH2:18][CH2:19][N:20]=[C:21]=[O:22]>>[Cl:17][CH2:18][CH2:19][NH:20][C:21]([N:16]([CH2:15][CH2:14][CH2:13][O:12][CH3:11])[CH:9]1[O:10][CH2:2][C@@H:3]([OH:4])[C@@H:5]([OH:6])[C@@H:7]1[OH:8])=[O:22]

Participants

Reactant 3

HCID 16723-Methoxypropylamine

HCID 160352-Chloroethyl isocyanate

HCID 66308D-Arabinose

Product 1

HCID 54230429HCID 54230429, compoundYield 76.6%

Procedure

3.0 g of D-arabinose, 3.6 g of 3-methoxy-n-propyl-amine and 3.0 g of 2-chloroethyl isocyanate are treated in the same manner as described in Example 13-(1). 5.0 g of 1-(2-chloroethyl)-3-(3-methoxy-n-propyl)-3-(D-arabinopyranosyl)-urea are thereby obtained as colorless caramel.

Sources & evidence

ORD record: ord-ed00f345e7f04ee6b563e4ef0ba21904
Source dataset: uspto-grants-1980_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04241053

Reaction notes

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